Deonte Banks returned an interception 98 yards on the final play as New York overcame a 14–3 deficit and improved to 3–1.

Green Bay survived two late red-zone turnovers and stopped Tampa Bay’s final drive to move to 2–2.

Trevor Lawrence threw for 227 yards and Jacksonville held off a late Cincinnati drive to improve to 3–1.

Baltimore built a 24–7 halftime lead and held on after Lamar Jackson left with an ankle injury, sending Tennessee to 0–4.

Kyren Williams scored twice in the final four minutes as Los Angeles erased a 20–10 halftime deficit in Philadelphia.

Kyle Monangai rushed for 146 yards and two touchdowns as Chicago held New York to 157 total yards in a 23–12 Week 4 win.

Bryce Young threw for 329 yards and Tetairoa McMillan caught 14 passes for 192 yards as Carolina beat Detroit 32–26 in Week 4.

San Francisco scored 21 second-half points and leaned on its defense to beat Denver 24–14, keeping the 49ers unbeaten at 4–0.

Seattle built a 27–6 advantage, forced four Justin Herbert turnovers and held off Los Angeles for a 30–23 Week 4 win.

Kansas City erased a fourth-quarter deficit and survived a late Las Vegas drive for a 30–27 road win, moving the Chiefs to 4–0.